Small molecules which mimic Celecoxib treatment
Canned Analysis
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General Information
AccessionDCA00011812
TitleSmall molecules which mimic Celecoxib treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Celecoxib treatment in the Primary Colorectal Adenocarcinoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e7e1e467bea600fb9720
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2458
Cell TypePrimary Colorectal Adenocarcinoma
Drug NameCelecoxib
DrugBank IDDB00482
Organismhuman
PubChem CID2662
SMILES IDCC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM283128, GSM283130, GSM283131, GSM283133, GSM283137, GSM283139, GSM283140, GSM283141, GSM283143, GSM283144, GSM283146, GSM283149
Perturbed SamplesGSM283127, GSM283129, GSM283132, GSM283134, GSM283135, GSM283136, GSM283138, GSM283142, GSM283145, GSM283147, GSM283148
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11237
Gene Expression Omnibus
Cyclooxygenase-2 inhibitor celecoxib effect on colorectal adenocarcinoma
19
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