Small molecules which reverse Tretinoin treatment
Canned Analysis
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General Information
AccessionDCA00011819
TitleSmall molecules which reverse Tretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Tretinoin treatment in the F9 teratocarcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e8f1e467bea600fb9798
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2460
Cell TypeF9 teratocarcinoma cells
Drug NameTretinoin
DrugBank IDDB00755
Organismmouse
PubChem CID444795
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM775291, GSM775295, GSM775299
Perturbed SamplesGSM775292, GSM775296, GSM775300
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE31280
Gene Expression Omnibus
All-trans retinoic acid effect on retinoic acid receptor -deficient F9 teratocarcinoma cells
21
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