Small molecules which mimic Tretinoin treatment
Canned Analysis
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General Information
AccessionDCA00011820
TitleSmall molecules which mimic Tretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Tretinoin treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e621e467bea600fb965c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2829
Drug NameTretinoin
DrugBank IDDB00755
Organismmouse
PubChem CID444795
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM775293, GSM775297, GSM775301
Perturbed SamplesGSM775294, GSM775298, GSM775302
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31280
Gene Expression Omnibus
All-trans retinoic acid effect on retinoic acid receptor -deficient F9 teratocarcinoma cells
21
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