Small molecules which reverse Tretinoin treatment
Canned Analysis
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General Information
AccessionDCA00011823
TitleSmall molecules which reverse Tretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Tretinoin treatment in the HL60 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e152e467bea600fb9442
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2461
Cell TypeHL60 cells
Drug NameTretinoin
DrugBank IDDB00755
Organismhuman
PubChem CID444795
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM112915, GSM112916, GSM112918
Perturbed SamplesGSM112919, GSM112920, GSM112921
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5007
Gene Expression Omnibus
Tretinoin effect on promyelocytic leukemia cell line
7
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