Small molecules which reverse Phenobarbital sodium treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00011825
TitleSmall molecules which reverse Phenobarbital sodium treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Phenobarbital sodium treatment in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e165e467bea600fb944a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2462
Cell Typeliver
Drug NamePhenobarbital sodium
Organismmouse
PubChem CID23674889
SMILES IDCCC1(C(=O)NC(=NC1=O)[O-])C2=CC=CC=C2.[Na+]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM154968, GSM154969, GSM154970, GSM154971
Perturbed SamplesGSM154964, GSM154965, GSM154966, GSM154967
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6721
Gene Expression Omnibus
Liver response to a high cholesterol diet and phenobarbital
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.