Small molecules which reverse Monuron treatment
Canned Analysis
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General Information
AccessionDCA00011835
TitleSmall molecules which reverse Monuron treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Monuron treatment in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e81be467bea600fb973a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2470
Cell TypeLiver
Drug NameMonuron
Organismrat
PubChem CID8800
SMILES IDCN(C)C(=O)NC1=CC=C(C=C1)Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1239955, GSM1239956, GSM1239957, GSM1239958
Perturbed SamplesGSM1239951, GSM1239952, GSM1239953, GSM1239954
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51163
Gene Expression Omnibus
Expression data from NRK-52E cells treated with monuron for 6h, 24h and 72h and rats exposed to monuron for 72h.
35
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