Small molecules which mimic Natural alpha interferon treatment
Canned Analysis
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General Information
AccessionDCA00011848
TitleSmall molecules which mimic Natural alpha interferon treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Natural alpha interferon treatment in the lung epithelial A549 cells, 24h treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e03ae467bea600fb93c4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2474
Cell Typelung epithelial A549 cells, 24h treatment
Drug NameNatural alpha interferon
DrugBank IDDB05258
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM128897, GSM128898, GSM128906, GSM128915
Perturbed SamplesGSM128894, GSM128903, GSM128907, GSM128912
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5542
Gene Expression Omnibus
Type I and Type II interferons effect on lung epithelial cell line: time course
28
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