Small molecules which mimic Interferon gamma-1b treatment
Canned Analysis
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General Information
AccessionDCA00011850
TitleSmall molecules which mimic Interferon gamma-1b treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Interferon gamma-1b treatment in the lung epithelial A549 cells, 6h treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e633e467bea600fb9664
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2476
Cell Typelung epithelial A549 cells, 6h treatment
Drug NameInterferon gamma-1b
DrugBank IDDB00033
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM128888, GSM128893, GSM128902, GSM128911
Perturbed SamplesGSM128885, GSM128891, GSM128900, GSM128909
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5542
Gene Expression Omnibus
Type I and Type II interferons effect on lung epithelial cell line: time course
28
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