Small molecules which reverse Cigarette smoke treatment
Canned Analysis
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General Information
AccessionDCA00011857
TitleSmall molecules which reverse Cigarette smoke treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Cigarette smoke treatment in the Alveolar Macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e357e467bea600fb9526
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2478
Cell TypeAlveolar Macrophages
Drug NameCigarette smoke
Organismhuman
PubChem CID57288536
SMILES IDC1=CC(=CC=C1N)S(=O)(=O)OC2=C(C=C(C=C2[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM219241, GSM219242, GSM219243, GSM219244, GSM219245, GSM219246, GSM219247, GSM219248, GSM219249, GSM219250, GSM219251
Perturbed SamplesGSM219252, GSM219253, GSM219254, GSM219255, GSM219256, GSM219257, GSM219258, GSM219259, GSM219260, GSM219261, GSM219262, GSM219263, GSM219264
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8823
Gene Expression Omnibus
Alveolar macrophages of cigarette smokers
7
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