Small molecules which reverse Colistin treatment
Canned Analysis
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General Information
AccessionDCA00011861
TitleSmall molecules which reverse Colistin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Colistin treatment in the C57BL/6J kidneys cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e607e467bea600fb9652
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2480
Cell TypeC57BL/6J kidneys
Drug NameColistin
DrugBank IDDB00803
Organismmouse
PubChem CID5311054
SMILES IDCCC(C)CCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC(C)C)CC(C)C)CCN)CCN)C(C)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1129870, GSM1129872, GSM1129874, GSM1129876, GSM1129878, GSM1129880
Perturbed SamplesGSM1129871, GSM1129873, GSM1129875, GSM1129877, GSM1129879, GSM1129881
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46410
Gene Expression Omnibus
Colistin effect on the kidney
7
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