Small molecules which reverse Ribavirin treatment
Canned Analysis
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General Information
AccessionDCA00011863
TitleSmall molecules which reverse Ribavirin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Ribavirin treatment in the uninfected hepatoma Huh7.5.1 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d2aee467bea600fb8dc6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2481
Cell Typeuninfected hepatoma Huh7.5.1 cells
Drug NameRibavirin
DrugBank IDDB00811
Organismhuman
PubChem CID37542
SMILES IDC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM568463, GSM568464, GSM568465
Perturbed SamplesGSM568466, GSM568467, GSM568468
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE23031
Gene Expression Omnibus
Ribavirin effect on uninfected hepatoma Huh7.5.1 cells
7
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