Small molecules which reverse Acetaminophen treatment
Canned Analysis
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General Information
AccessionDCA00011865
TitleSmall molecules which reverse Acetaminophen treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Acetaminophen treatment in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ea5ae467bea600fb9834
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2482
Cell TypeLiver
Drug NameAcetaminophen
DrugBank IDDB00316
Organismmouse
PubChem CID1983
SMILES IDCC(=O)NC1=CC=C(C=C1)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM929282, GSM929283, GSM929284
Perturbed SamplesGSM929285, GSM929286, GSM929287
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37874
Gene Expression Omnibus
Acetaminophen effect on thioredoxin reductase 1-null liver
21
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