Small molecules which mimic Laccaic acid treatment
Canned Analysis
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General Information
AccessionDCA00011880
TitleSmall molecules which mimic Laccaic acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Laccaic acid treatment in the MCF-7 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec3de467bea600fb990a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdrug:2490
Cell TypeMCF-7 breast cancer cells
Drug NameLaccaic acid
Organismhuman
PubChem CID5355255
SMILES IDCCC1=C(C2=C(C(=C1C(=O)C)O)C(=O)C3=C(C(=C(C=C3C2=O)O)C(=O)O)C(=O)O)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1115765, GSM1115767, GSM1115769
Perturbed SamplesGSM1115766, GSM1115768, GSM1115770
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45804
Gene Expression Omnibus
Laccaic acid effect on breast cancer cell line
12
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