Small molecules which mimic Sunitinib treatment
Canned Analysis
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General Information
AccessionDCA00011882
TitleSmall molecules which mimic Sunitinib treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Sunitinib treatment in the liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec45e467bea600fb990e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormmluxy
CREEDS IDdrug:2491
Cell Typeliver tissue
Drug NameSunitinib
DrugBank IDDB01268
Organismrat
PubChem CID5329102
SMILES IDCCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM159830, GSM159833, GSM159834, GSM159835
Perturbed SamplesGSM159831, GSM159832, GSM159837, GSM159838
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6929
Gene Expression Omnibus
Cirrhotic liver response to the antiangiongenic agent Sunitinib
7
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