Small molecules which reverse Alfacalcidol treatment
Canned Analysis
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General Information
AccessionDCA00011891
TitleSmall molecules which reverse Alfacalcidol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Alfacalcidol treatment in the RWPE1 - Prostate epithelial cell line - 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d615e467bea600fb8f46
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3363
Cell TypeRWPE1 - Prostate epithelial cell line - 24 Hours
Drug NameAlfacalcidol
DrugBank IDDB01436
Organismhuman
PubChem CID5282181
SMILES IDCC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM400059, GSM400060, GSM400061, GSM400062
Perturbed SamplesGSM400063, GSM400064, GSM400065, GSM400066
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15947
Gene Expression Omnibus
1,25 dihydroxyvitamin D effect on prostate epithelial cell line RWPE1: time course
28
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