Small molecules which mimic Hodgkin lymphoma treatment
Canned Analysis
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General Information
AccessionDCA00011894
TitleSmall molecules which mimic Hodgkin lymphoma treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Hodgkin lymphoma treatment in the L-540 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec5fe467bea600fb991a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2494
Cell TypeL-540
Drug NameHodgkin lymphoma
Organismhuman
PubChem CID148177
SMILES IDCCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM769260, GSM769261, GSM769262
Perturbed SamplesGSM769263, GSM769264, GSM769265
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31059
Gene Expression Omnibus
Gene expression profiling of L-540 Hodgkin lymphoma cell line after in vitro and in vivo treatment with perifosine in combination with sorafenib
7
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