Small molecules which mimic Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00011902
TitleSmall molecules which mimic Decitabine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Decitabine treatment in the HepG2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec71e467bea600fb9922
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2497
Cell TypeHepG2
Drug NameDecitabine
DrugBank IDDB01262
Organismhuman
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM118418, GSM118419, GSM118420, GSM118421
Perturbed SamplesGSM118422, GSM118423, GSM118424, GSM118425
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5230
Gene Expression Omnibus
Hepatoma cell response to inhibition of DNA methylation and histone deacetylation
7
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