Small molecules which reverse Celecoxib treatment
Canned Analysis
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General Information
AccessionDCA00011911
TitleSmall molecules which reverse Celecoxib treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Celecoxib treatment in the AGS cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1db73e467bea600fb91aa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdrug:2501
Cell TypeAGS cells
Drug NameCelecoxib
DrugBank IDDB00482
Organismhuman
PubChem CID2662
SMILES IDCC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1321413, GSM1321414, GSM1321415
Perturbed SamplesGSM1321416, GSM1321417, GSM1321418
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54657
Gene Expression Omnibus
Celecoxib induced transcriptional alterations in gastric cancer cells
7
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