Small molecules which mimic Mepenzolate bromide treatment
Canned Analysis
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General Information
AccessionDCA00011912
TitleSmall molecules which mimic Mepenzolate bromide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Mepenzolate bromide treatment in the lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1db56e467bea600fb919c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:2502
Cell Typelung
Drug NameMepenzolate bromide
Organismmouse
PubChem CID6461
SMILES IDC[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1230990, GSM1230991
Perturbed SamplesGSM1230986, GSM1230987
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50836
Gene Expression Omnibus
Mepenzolate bromide effect on lung: time course
21
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