Small molecules which reverse Mepenzolate treatment
Canned Analysis
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General Information
AccessionDCA00011915
TitleSmall molecules which reverse Mepenzolate treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Mepenzolate treatment in the Lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dd19e467bea600fb9266
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDdrug:2530
Cell TypeLung
Drug NameMepenzolate
DrugBank IDDB04843
Organismmouse
PubChem CID4057
SMILES IDC[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1230992, GSM1230993
Perturbed SamplesGSM1230988, GSM1230989
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50836
Gene Expression Omnibus
Mepenzolate bromide effect on lung: time course
21
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