Small molecules which mimic Fenretinide treatment
Canned Analysis
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General Information
AccessionDCA00011952
TitleSmall molecules which mimic Fenretinide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Fenretinide treatment in the CD34+ CML cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb4ae467bea600fb989a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2529
Cell TypeCD34+ CML cells
Drug NameFenretinide
DrugBank IDDB05076
Organismhuman
SMILES IDO=C(Nc1ccc(cc1)O)/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM435978, GSM435979, GSM435980
Perturbed SamplesGSM435981, GSM435982, GSM435983, GSM435984, GSM435985
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17480
Gene Expression Omnibus
Transcriptome profiling of fenretinide-treated and untreated CD34+ cells from 4 CML patients
7
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