Small molecules which reverse Cisplatin treatment
Canned Analysis
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General Information
AccessionDCA00011955
TitleSmall molecules which reverse Cisplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Cisplatin treatment in the A549 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dd0fe467bea600fb9262
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatoralanstern
CREEDS IDdrug:2532
Cell TypeA549
Drug NameCisplatin
DrugBank IDDB00515
Organismhuman
PubChem CID441203
SMILES IDN.N.Cl[Pt+2]Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM147889, GSM147890, GSM147891
Perturbed SamplesGSM147892, GSM147893, GSM147894
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6410
Gene Expression Omnibus
Non-small cell lung carcinoma cell line response to cisplatin
7
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