Small molecules which mimic Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00011966
TitleSmall molecules which mimic Decitabine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Decitabine treatment in the A549 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dd43e467bea600fb9278
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:2539
Cell TypeA549
Drug NameDecitabine
DrugBank IDDB01262
Organismhuman
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM720475, GSM720476
Perturbed SamplesGSM720485, GSM720486
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29077
Gene Expression Omnibus
Expression data comparing azacitidine and decitabine in non-small cell lung cancer lines
84
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