Small molecules which mimic Plx4032 treatment
Canned Analysis
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General Information
AccessionDCA00012000
TitleSmall molecules which mimic Plx4032 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Plx4032 treatment in the WM164 BRAF mutant Melanoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef0ee467bea600fb9a4a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2556
Cell TypeWM164 BRAF mutant Melanoma cells
Drug NamePlx4032
DrugBank IDDB05238
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1322672, GSM1322673, GSM1322674
Perturbed SamplesGSM1322675, GSM1322676, GSM1322677
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE54711
Gene Expression Omnibus
Parent vs. Induced drug tolerant cells Microarray Analysis
7
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