Small molecules which reverse Plx4032 treatment
Canned Analysis
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General Information
AccessionDCA00012021
TitleSmall molecules which reverse Plx4032 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Plx4032 treatment in the M249_R4 melanoma resistant sub-line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d65ee467bea600fb8f66
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2566
Cell TypeM249_R4 melanoma resistant sub-line
Drug NamePlx4032
DrugBank IDDB05238
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM611400, GSM611402
Perturbed SamplesGSM611412, GSM611414
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24862
Gene Expression Omnibus
Expression data from melanoma cell lines
42
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