Small molecules which reverse Plx4032 treatment
Canned Analysis
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General Information
AccessionDCA00012027
TitleSmall molecules which reverse Plx4032 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Plx4032 treatment in the M238 melanoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb55e467bea600fb98a0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2569
Cell TypeM238 melanoma cell line
Drug NamePlx4032
DrugBank IDDB05238
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM611406, GSM611408
Perturbed SamplesGSM611418, GSM611420
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24862
Gene Expression Omnibus
Expression data from melanoma cell lines
42
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