Small molecules which mimic Rituximab treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012042
TitleSmall molecules which mimic Rituximab treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Rituximab treatment in the CD19+ selected B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d473e467bea600fb8e8c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdrug:2577
Cell TypeCD19+ selected B cells
Drug NameRituximab
DrugBank IDDB00073
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM388583, GSM388584, GSM388585, GSM388586, GSM388587, GSM388588, GSM388589, GSM388590, GSM388591, GSM388592
Perturbed SamplesGSM388593, GSM388594, GSM388595, GSM388596, GSM388597, GSM388598, GSM388599, GSM388600, GSM388601, GSM388602
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15490
Gene Expression Omnibus
Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy effect on chronic lymphocytic leukemia
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.