Small molecules which mimic Pd173074 treatment
Canned Analysis
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General Information
AccessionDCA00012044
TitleSmall molecules which mimic Pd173074 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Pd173074 treatment in the MGHU3 bladder cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d4f2e467bea600fb8ec4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2578
Cell TypeMGHU3 bladder cancer cells
Drug NamePd173074
Organismhuman
PubChem CID1401
SMILES IDCCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1267150, GSM1267151, GSM1267152
Perturbed SamplesGSM1267153, GSM1267154, GSM1267155
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52452
Gene Expression Omnibus
Fibroblast growth factor receptor inhibition effect on malignant urothelial cells deficient in TGF-activated kinase 1
33
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