Small molecules which mimic Tamoxifen treatment
Canned Analysis
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General Information
AccessionDCA00012048
TitleSmall molecules which mimic Tamoxifen treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Tamoxifen treatment in the pancreas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e892e467bea600fb976e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdrug:2579
Cell Typepancreas
Drug NameTamoxifen
DrugBank IDDB00675
Organismmouse
PubChem CID2733526
SMILES IDCCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM845195, GSM845196, GSM845197, GSM845198
Perturbed SamplesGSM845203, GSM845204, GSM845205, GSM845206
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34232
Gene Expression Omnibus
Transcription factor MIST1-null and MIST1-induced pancreas
14
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