Small molecules which mimic Pioglitazone treatment
Canned Analysis
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General Information
AccessionDCA00012068
TitleSmall molecules which mimic Pioglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Pioglitazone treatment in the 3T3-L1 adipocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e1d8e467bea600fb947c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2587
Cell Type3T3-L1 adipocytes
Drug NamePioglitazone
DrugBank IDDB01132
Organismmouse
PubChem CID4829
SMILES IDCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM24459, GSM24460, GSM24461
Perturbed SamplesGSM24462, GSM24463
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1458
Gene Expression Omnibus
Thiazolidinedione treatment of 3T3-L1 adipocytes
21
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