Small molecules which reverse Rosiglitazone treatment
Canned Analysis
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General Information
AccessionDCA00012071
TitleSmall molecules which reverse Rosiglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Rosiglitazone treatment in the 3T3-L1 adipocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e7a3e467bea600fb9706
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2588
Cell Type3T3-L1 adipocytes
Drug NameRosiglitazone
Organismmouse
PubChem CID77999
SMILES IDCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM24459, GSM24460, GSM24461
Perturbed SamplesGSM24464, GSM24465, GSM24466
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1458
Gene Expression Omnibus
Thiazolidinedione treatment of 3T3-L1 adipocytes
21
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