Small molecules which reverse Etanercept treatment
Canned Analysis
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General Information
AccessionDCA00012079
TitleSmall molecules which reverse Etanercept treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Etanercept treatment in the plaque on epidermis cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb14e467bea600fb9884
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:2592
Cell Typeplaque on epidermis
Drug NameEtanercept
DrugBank IDDB00005
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1155752, GSM1155757, GSM1155763, GSM1155769, GSM1155775, GSM1155780
Perturbed SamplesGSM1155754, GSM1155759, GSM1155765, GSM1155771, GSM1155782
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE47751
Gene Expression Omnibus
Early tissue responses to etanercept in psoriasis lesions
28
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