Small molecules which mimic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012084
TitleSmall molecules which mimic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment in the cultured molar teeth from embryonic day 14 fetuses cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d577e467bea600fb8f00
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2595
Cell Typecultured molar teeth from embryonic day 14 fetuses
Drug Name2,3,7,8-tetrachlorodibenzo-p-dioxin
Organismmouse
PubChem CID15625
SMILES IDC1=C2C(=CC(=C1Cl)Cl)OC3=CC(=C(C=C3O2)Cl)Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM109312, GSM109590
Perturbed SamplesGSM109592, GSM109593
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4873
Gene Expression Omnibus
2,3,7,8-tetrachlorodibenzo-p-dioxin effect on cultured embryonic teeth
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.