Small molecules which mimic Etanercept treatment
Canned Analysis
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General Information
AccessionDCA00012086
TitleSmall molecules which mimic Etanercept treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Etanercept treatment in the whole-blood leukocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d5a5e467bea600fb8f14
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:2596
Cell Typewhole-blood leukocytes
Drug NameEtanercept
DrugBank IDDB00005
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM882389, GSM882391, GSM882393, GSM882395, GSM882397, GSM882399, GSM882401
Perturbed SamplesGSM882403, GSM882405, GSM882407, GSM882409, GSM882411, GSM882413, GSM882415, GSM882417
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE36177
Gene Expression Omnibus
Genome-wide gene expression analysis of the whole blood leukocyte transcriptional response to endotoxin treatment
14
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