Small molecules which reverse Methamphetamine treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012115
TitleSmall molecules which reverse Methamphetamine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Methamphetamine treatment in the striatum, day 6 treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb0be467bea600fb9880
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2614
Cell Typestriatum, day 6 treatment
Drug NameMethamphetamine
DrugBank IDDB01577
Organismmouse
PubChem CID10836
SMILES IDCC(CC1=CC=CC=C1)NC
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM751162, GSM751197, GSM751215
Perturbed SamplesGSM751191, GSM751203, GSM751227
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30305
Gene Expression Omnibus
Transcriptional effects of chronic heroin and methamphetamine treatment in the mouse striatum
63
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.