Small molecules which mimic Methamphetamine treatment
Canned Analysis
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General Information
AccessionDCA00012116
TitleSmall molecules which mimic Methamphetamine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Methamphetamine treatment in the striatum, day 12 treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eae3e467bea600fb986e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2616
Cell Typestriatum, day 12 treatment
Drug NameMethamphetamine
DrugBank IDDB01577
Organismmouse
PubChem CID10836
SMILES IDCC(CC1=CC=CC=C1)NC
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM751180, GSM751210, GSM751234
Perturbed SamplesGSM751168, GSM751186, GSM751216
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30305
Gene Expression Omnibus
Transcriptional effects of chronic heroin and methamphetamine treatment in the mouse striatum
63
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