Small molecules which reverse Methamphetamine treatment
Canned Analysis
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General Information
AccessionDCA00012119
TitleSmall molecules which reverse Methamphetamine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Methamphetamine treatment in the striatum, day 15 withdrawal cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e5dde467bea600fb9642
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2621
Cell Typestriatum, day 15 withdrawal
Drug NameMethamphetamine
DrugBank IDDB01577
Organismmouse
PubChem CID10836
SMILES IDCC(CC1=CC=CC=C1)NC
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM751170, GSM751205, GSM751229
Perturbed SamplesGSM751211, GSM751223, GSM751235
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30305
Gene Expression Omnibus
Transcriptional effects of chronic heroin and methamphetamine treatment in the mouse striatum
63
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