Small molecules which reverse Fluoxetine treatment
Canned Analysis
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General Information
AccessionDCA00012131
TitleSmall molecules which reverse Fluoxetine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Fluoxetine treatment in the hippocampus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e384e467bea600fb953a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2618
Cell Typehippocampus
Drug NameFluoxetine
Organismmouse
PubChem CID62857
SMILES IDCNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM148900, GSM148901
Perturbed SamplesGSM148902, GSM148903
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6476
Gene Expression Omnibus
Fluoxetine effect on the hippocampus
7
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