Small molecules which mimic Soman treatment
Canned Analysis
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General Information
AccessionDCA00012154
TitleSmall molecules which mimic Soman treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Soman treatment in the Hippocampus (of Sprauge-Dawley males) - 24 Hours after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e83ce467bea600fb974a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:2635
Cell TypeHippocampus (of Sprauge-Dawley males) - 24 Hours after exposure
Drug NameSoman
Organismrat
PubChem CID7305
SMILES IDCC(C(C)(C)C)OP(=O)(C)F
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM338857, GSM338858, GSM338859
Perturbed SamplesGSM338878, GSM338879, GSM338881
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13428
Gene Expression Omnibus
Hippocampus response to acetylcholinesterase inhibitor soman: time course
56
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