Small molecules which mimic Rosiglitazone treatment
Canned Analysis
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General Information
AccessionDCA00012226
TitleSmall molecules which mimic Rosiglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Rosiglitazone treatment in the left sciatic nerve cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d0fbe467bea600fb8d08
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:2672
Cell Typeleft sciatic nerve
Drug NameRosiglitazone
Organismmouse
PubChem CID77999
SMILES IDCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM286159, GSM286160, GSM286163, GSM286165
Perturbed SamplesGSM286431, GSM286432, GSM286433, GSM286434, GSM286436
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11343
Gene Expression Omnibus
Rosiglitazone effect on streptozotocin-induced diabetic DBA/2J mice: perpheral sciatic nerve
26
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