Small molecules which reverse Rosiglitazone treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012231
TitleSmall molecules which reverse Rosiglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Rosiglitazone treatment in the perpheral sciatic nerve cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e67fe467bea600fb9686
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3255
Cell Typeperpheral sciatic nerve
Drug NameRosiglitazone
DrugBank IDDB00412
Organismmouse
SMILES IDO=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM286431, GSM286432, GSM286433, GSM286434, GSM286436
Perturbed SamplesGSM286159, GSM286160, GSM286163, GSM286165
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11343
Gene Expression Omnibus
Rosiglitazone effect on streptozotocin-induced diabetic DBA/2J mice: perpheral sciatic nerve
26
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.