Small molecules which reverse Amoxicillin treatment
Canned Analysis
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General Information
AccessionDCA00012255
TitleSmall molecules which reverse Amoxicillin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Amoxicillin treatment in the colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ed91e467bea600fb99a4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2678
Cell Typecolon
Drug NameAmoxicillin
DrugBank IDDB01060
Organismrat
PubChem CID33613
SMILES IDCC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM42548, GSM42549, GSM42550, GSM42551, GSM42552
Perturbed SamplesGSM42527, GSM42528, GSM42529, GSM42530, GSM42532, GSM42533
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2354
Gene Expression Omnibus
Amoxicillin effect on small intestine and colon development: time course
21
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