Small molecules which mimic Bexarotene treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012256
TitleSmall molecules which mimic Bexarotene treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Bexarotene treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e8f7e467bea600fb979a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2680
Drug NameBexarotene
DrugBank IDDB00307
Organismhuman
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM159355, GSM159356, GSM159357, GSM159358
Perturbed SamplesGSM159359, GSM159360, GSM159361, GSM159362
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6914
Gene Expression Omnibus
Bexarotene effect on gemcitabine resistant non-small lung cancer cell line
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.