Small molecules which reverse Bexarotene treatment
Canned Analysis
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General Information
AccessionDCA00012259
TitleSmall molecules which reverse Bexarotene treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Bexarotene treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d529e467bea600fb8ede
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2681
Drug NameBexarotene
DrugBank IDDB00307
Organismhuman
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM320837, GSM320841, GSM320845, GSM320849
Perturbed SamplesGSM320838, GSM320842, GSM320846, GSM320850
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12791
Gene Expression Omnibus
Acquired paclitaxel-resistant MDA-MB-231 cancer cells response to bexarotene treatment
14
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