Small molecules which mimic Cisplatin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012272
TitleSmall molecules which mimic Cisplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cisplatin treatment in the Embryonic FIBROLAST - Rb null mutant cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e2aae467bea600fb94d8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3412
Cell TypeEmbryonic FIBROLAST - Rb null mutant
Drug NameCisplatin
DrugBank IDDB00515
Organismmouse
PubChem CID441203
SMILES IDN.N.Cl[Pt+2]Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM143373, GSM143374, GSM143375
Perturbed SamplesGSM143376, GSM143377, GSM143378
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6206
Gene Expression Omnibus
Rb null mutant embryonic fibroblast response to cisplatin
21
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.