Small molecules which mimic Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00012286
TitleSmall molecules which mimic Decitabine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Decitabine treatment in the melanoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef4de467bea600fb9a66
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2703
Cell Typemelanoma
Drug NameDecitabine
DrugBank IDDB01262
Organismhuman
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM230901, GSM230903, GSM230905, GSM230907, GSM230909, GSM230911
Perturbed SamplesGSM230902, GSM230904, GSM230906, GSM230908, GSM230910, GSM230912
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9118
Gene Expression Omnibus
DNA methylation inhibitor effect on melanoma cell lines
7
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