Small molecules which reverse Dexamethasone treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012289
TitleSmall molecules which reverse Dexamethasone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Dexamethasone treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1de4de467bea600fb92ee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2709
Drug NameDexamethasone
DrugBank IDDB01234
Organismmouse
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM124988, GSM124989
Perturbed SamplesGSM124990, GSM124991
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5463
Gene Expression Omnibus
CD4/CD8 double positive thymocyte response to glucocorticoid
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.