Small molecules which mimic Dexamethasone treatment
Canned Analysis
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General Information
AccessionDCA00012292
TitleSmall molecules which mimic Dexamethasone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Dexamethasone treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dda8e467bea600fb92a4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2711
Drug NameDexamethasone
DrugBank IDDB01234
Organismmouse
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM4141, GSM4142
Perturbed SamplesGSM4139, GSM4140
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE484
Gene Expression Omnibus
Alveoli septation inhibition and protection
14
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