Small molecules which mimic Dexamethasone treatment
Canned Analysis
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General Information
AccessionDCA00012302
TitleSmall molecules which mimic Dexamethasone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Dexamethasone treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1da47e467bea600fb9124
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2714
Drug NameDexamethasone
DrugBank IDDB01234
Organismhuman
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM847200, GSM847201, GSM847202, GSM847203
Perturbed SamplesGSM847204, GSM847205, GSM847206
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE34313
Gene Expression Omnibus
Dexamethasone effect on cultured airway smooth muscle cells: time course
14
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