Small molecules which reverse Diethylstilbestrol treatment
Canned Analysis
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General Information
AccessionDCA00012311
TitleSmall molecules which reverse Diethylstilbestrol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Diethylstilbestrol treatment in the brown norway cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ddbae467bea600fb92ae
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2717
Cell Typebrown norway
Drug NameDiethylstilbestrol
DrugBank IDDB00255
Organismrat
PubChem CID448537
SMILES IDCCC(=C(CC)C1=CC=C(C=C1)O)C2=CC=C(C=C2)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM92214, GSM92215, GSM92216
Perturbed SamplesGSM92217, GSM92218, GSM92219, GSM92220
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4028
Gene Expression Omnibus
Diethylstilbestrol effect on pituitary glands of males of various inbred strains
21
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